4-苯基-1(2H)-酞嗪酮合成路线 （共 19 条）
反应条件
hydrogenchloride; aluminium trichloride Heatingother N-aminophthalimides, other aryls; Mechanism;
参考文献
Ismail, Mohamed Fekry; Kandile, Nadia Gharib
Acta Chimica Hungarica, 1991 , vol. 128, # 2 p. 251 - 253
反应条件
1: 93 percent / AlCl3 / 2 h / Heating 2: 95 percent / H2NNH2*H2O / 2 h / 100 °C View Scheme
参考文献
Ismail, Mohamed Fekry; Kandile, Nadia Gharib
Acta Chimica Hungarica, 1991 , vol. 128, # 2 p. 251 - 253
反应条件
1.) C6H6, Et2O, THF, 3 deg C; 2.) MeOH, reflux, 30 min; Yield given. Multistep reaction;
参考文献
Breukelman, Stephen P.; Meakins, G. Denis
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1627 - 1636
参考文献
Bednjagina; Postowskii
Zhurnal Obshchei Khimii, 1956 , vol. 26, p. 2279,2283; engl. Ausg. S. 2549, 2552
反应条件
trichlorophosphate T=85°C; 4 h;
参考文献
Rival, Yveline; Hoffmann, Remy; Didier, Bruno; Rybaltchenko, Volodymyr; Bourguignon, Jean-Jacques; Wermuth, Camille G.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 3 p. 311 - 317
反应条件
tetraphosphorus decasulfide; triethylamine in acetonitrile 1 h; Reflux;
参考文献
Hemdan, Magdy M.; Taha, Sherif M.; Gabr, Adel M.; Elkady, Mohamed Y.
Journal of Chemical Research, 2010 , # 2 p. 102 - 105
反应条件
N-benzyl-trimethylammonium hydroxide in 1,4-dioxane
T=120°C; 3 h; Yield given;
参考文献
Yamada; Nobuhara; Yamaguchi; Ohki
Journal of Medicinal Chemistry, 1982 , vol. 25, # 8 p. 975 - 982
反应条件
1: Triton-B (40percent in methanol) / dioxane / 3 h / 120 °C
2: 10percent aq. KOH / 7 h / Heating
View Scheme
参考文献
Merchant, J. R.; Kulkarni, S. D.; Venkatesh, M. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 10 p. 914 - 916
反应条件
hydrogenchloride; zinc
Reduction; 1 h; Heating;
参考文献
Botero Cid, Hector M.; Traenkle, Christian; Baumann, Knut; Pick, Rainer; Mies-Klomfass, Elisabeth; Kostenis, Evi; Mohr, Klaus; Holzgrabe, Ulrike
Journal of Medicinal Chemistry, 2000 , vol. 43, # 11 p. 2155 - 2164
