6-氯-9-异丙基-9H-嘌呤合成路线 （共 5 条）
反应条件
di-isopropyl azodicarboxylate; triphenylphosphine in tetrahydrofuran
T=70°C; Mitsunobu coupling; 12 h;
参考文献
Lu, Weibing; Sengupta, Sujata; Petersen, Jeffrey L.; Akhmedov, Novruz G.; Shi, Xiaodong
Journal of Organic Chemistry, 2007 , vol. 72, # 13 p. 5012 - 5015
反应条件
sulfuryl dichloride in dichloromethane; acetonitrile
T=0°C; 0.5 h;
参考文献
Ham, Young Jin; Lee, Duck-Hyung; Choi, Hwan Geun; Hah, Jung-Mi; Sim, Taebo
Tetrahedron Letters, 2010 , vol. 51, # 35 p. 4609 - 4611
反应条件
ethanesulfonic acid
68 h; Ambient temperature;
参考文献
Kelley, James L.; Morris Bullock; Krochmal, Mark P.; McLean, Ed W.; Linn, James A.; Durcan, Micheal J.; Cooper, Barrett R.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 20 p. 3207 - 3216
反应条件
sodium hydride in N,N-dimethyl-formamide
T=20°C;
参考文献
Kim, Bok Young; Ahn, Joong Bok; Lee, Hong Woo; Kang, Sung Kwon; Lee, Jung Hwa; Shin, Jae Soo; Ahn, Soon Kil; Hong, Chung Il; Yoon, Seung Soo
European Journal of Medicinal Chemistry, 2004 , vol. 39, # 5 p. 433 - 447
反应条件
in N,N-dimethyl-formamide
参考文献
Ustau Experimentalni Botaniky AV-CR
Patent: US6552192 B1, 2003 ;
