6-羟基烟酸合成路线

参考文献

Mulder, Jason A.; Frutos, Rogelio P.; Patel, Nitinchandra D.; Qu, Bo; Sun, Xiufeng; Tampone, Thomas G.; Gao, Joe; Sarvestani, Max; Eriksson, Magnus C.; Haddad, Nizar; Shen, Sherry; Song, Jinhua J.; Senanayake, Chris H.
Organic Process Research and Development, 2013 , vol. 17, # 6 p. 940 - 945

5006-66-66-羟基烟酸

73781-91-66-氯烟酸甲酯+

56055-54-05,6-二氯烟酸甲酯

参考文献

Mulder, Jason A.; Frutos, Rogelio P.; Patel, Nitinchandra D.; Qu, Bo; Sun, Xiufeng; Tampone, Thomas G.; Gao, Joe; Sarvestani, Max; Eriksson, Magnus C.; Haddad, Nizar; Shen, Sherry; Song, Jinhua J.; Senanayake, Chris H.
Organic Process Research and Development, 2013 , vol. 17, # 6 p. 940 - 945

5006-66-66-羟基烟酸

33252-28-76-氯-3-氰基吡啶

参考文献

Forrest; Walker
Journal of the Chemical Society, 1948 , p. 1939,1942

5006-66-66-羟基烟酸

41668-13-75-溴-6-羟基烟酸

参考文献

Roever, Stephan; Andjelkovic, Mirjana; Benardeau, Agnes; Chaput, Evelyne; Guba, Wolfgang; Hebeisen, Paul; Mohr, Susanne; Nettekoven, Matthias; Obst, Ulrike; Richter, Wolfgang F.; Ullmer, Christoph; Waldmeier, Pius; Wright, Matthew B.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 24 p. 9874 - 9896

5006-66-66-羟基烟酸+

100-39-0溴化苄

4332-79-01-苄基-6-氧代-1,6-二氢-3-吡啶羧酸

参考文献

ENCYSIVE PHARMACEUTICALS, INC.
Patent: WO2008/79371 A1, 2008 ;
Location in patent: Page/Page column 110 ;
WO 2008/079371 A1

5006-66-66-羟基烟酸

222970-60-75-氨基-6-羟基烟酸甲酯

参考文献

Linn, James A.; Gerritz, Samuel W.; Handlon, Anthony L.; Hyman, Clifton E.; Heyer, Dennis
Tetrahedron Letters, 1999 , vol. 40, # 12 p. 2227 - 2230

5006-66-66-羟基烟酸

59-67-6烟酸

参考文献

v. Pechmann; Welsh
Chemische Berichte, 1884 , vol. 17, p. 2394

5006-66-66-羟基烟酸

365413-29-26-氯-5-碘烟酸甲酯

参考文献

Dott, Pascal; Waldmeier, Pius
Patent: US2012/101282 A1, 2012 ;

5006-66-66-羟基烟酸

23312-67-6

参考文献

Frister, Hermann; Kemper, Klaus; Boos, Karl-Siegfried; Schlimme, Eckhard
Liebigs Annalen der Chemie, 1985 , # 3 p. 510 - 516

5006-66-66-羟基烟酸

78686-77-85-溴-6-氯烟酸甲酯

参考文献

Roever, Stephan; Andjelkovic, Mirjana; Benardeau, Agnes; Chaput, Evelyne; Guba, Wolfgang; Hebeisen, Paul; Mohr, Susanne; Nettekoven, Matthias; Obst, Ulrike; Richter, Wolfgang F.; Ullmer, Christoph; Waldmeier, Pius; Wright, Matthew B.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 24 p. 9874 - 9896