6-羟基烟酸合成路线

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Bigge, Christopher Franklin; Bridges, Alexander James; Casimiro-Garcia, Agustin; Fakhoury, Stephen Alan; Lee, Helen Tsenwhei; Reed, Jessica; Schaum, Robert; Schlosser, Kevin Matthew; Sexton, Karen; Zhou, Hairong
Patent: US2003/171377 A1, 2003 ;

5006-66-66-羟基烟酸

73781-91-66-氯烟酸甲酯+

56055-54-05,6-二氯烟酸甲酯

参考文献

Mulder, Jason A.; Frutos, Rogelio P.; Patel, Nitinchandra D.; Qu, Bo; Sun, Xiufeng; Tampone, Thomas G.; Gao, Joe; Sarvestani, Max; Eriksson, Magnus C.; Haddad, Nizar; Shen, Sherry; Song, Jinhua J.; Senanayake, Chris H.
Organic Process Research and Development, 2013 , vol. 17, # 6 p. 940 - 945

5006-66-66-羟基烟酸

73781-91-66-氯烟酸甲酯+

1360952-35-76-氯-5-(三氟甲基)-3-吡啶羧酸甲酯

参考文献

Mulder, Jason A.; Frutos, Rogelio P.; Patel, Nitinchandra D.; Qu, Bo; Sun, Xiufeng; Tampone, Thomas G.; Gao, Joe; Sarvestani, Max; Eriksson, Magnus C.; Haddad, Nizar; Shen, Sherry; Song, Jinhua J.; Senanayake, Chris H.
Organic Process Research and Development, 2013 , vol. 17, # 6 p. 940 - 945

5006-66-66-羟基烟酸

73781-91-66-氯烟酸甲酯

参考文献

Mulder, Jason A.; Frutos, Rogelio P.; Patel, Nitinchandra D.; Qu, Bo; Sun, Xiufeng; Tampone, Thomas G.; Gao, Joe; Sarvestani, Max; Eriksson, Magnus C.; Haddad, Nizar; Shen, Sherry; Song, Jinhua J.; Senanayake, Chris H.
Organic Process Research and Development, 2013 , vol. 17, # 6 p. 940 - 945

5006-66-66-羟基烟酸+

74-88-4甲基碘

66572-55-26-甲氧基烟酸

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Kozikowski; Xia; Reddy; Tuckmantel; Hanin; Tang
Journal of Organic Chemistry, 1991 , vol. 56, # 15 p. 4636 - 4645

5006-66-66-羟基烟酸

1012792-55-06-氯-5-(4-氯苯基)-3-吡啶羧酸甲酯

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Roever, Stephan; Andjelkovic, Mirjana; Benardeau, Agnes; Chaput, Evelyne; Guba, Wolfgang; Hebeisen, Paul; Mohr, Susanne; Nettekoven, Matthias; Obst, Ulrike; Richter, Wolfgang F.; Ullmer, Christoph; Waldmeier, Pius; Wright, Matthew B.
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5006-66-66-羟基烟酸

1007-18-7N-甲基-6-氧代-1H-吡啶-3-甲酰胺

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Hirota, Kosaku; Kitade, Yukio; Shimada, Kaoru; Maki, Yoshifumi
Journal of Organic Chemistry, 1985 , vol. 50, # 9 p. 1512 - 1516

5006-66-66-羟基烟酸+

64-17-5乙醇

18617-50-06-羟基烟酸乙酯

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KOWA COMPANY, LTD.
Patent: US2010/48610 A1, 2010 ;
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US 20100048610 A1

5006-66-66-羟基烟酸+

74-88-4甲基碘

3719-45-71-甲基-6-氧代-1,6-二氢吡啶-3-羧酸

参考文献

ALMIRALL, S.A.; GRIMA POVEDA, Pedro Manuel; AGUILAR IZQUIERDO, Nuria; MIR CEPEDA, Marta; LOPEZ MARTINEZ, Manuel
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WO 2010/043377 A1

5006-66-66-羟基烟酸

3719-45-71-甲基-6-氧代-1,6-二氢吡啶-3-羧酸

参考文献

v. Pechmann; Welsh
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