6-羟基烟酸合成路线

参考文献

Ling; Hong; Gonzalez; Gregor; Polinsky; Kuki; Shi; Teston; Murphy; Porter; Kiel; Lakis; Anderes; May; Knudsen; Lau
Journal of Medicinal Chemistry, 2001 , vol. 44, # 19 p. 3141 - 3149

5006-66-66-羟基烟酸

101990-70-95-氯甲基-2-甲氧基吡啶

参考文献

Kozikowski; Xia; Reddy; Tuckmantel; Hanin; Tang
Journal of Organic Chemistry, 1991 , vol. 56, # 15 p. 4636 - 4645

5006-66-66-羟基烟酸

1360952-35-76-氯-5-(三氟甲基)-3-吡啶羧酸甲酯

参考文献

Mulder, Jason A.; Frutos, Rogelio P.; Patel, Nitinchandra D.; Qu, Bo; Sun, Xiufeng; Tampone, Thomas G.; Gao, Joe; Sarvestani, Max; Eriksson, Magnus C.; Haddad, Nizar; Shen, Sherry; Song, Jinhua J.; Senanayake, Chris H.
Organic Process Research and Development, 2013 , vol. 17, # 6 p. 940 - 945

5006-66-66-羟基烟酸

1360952-35-76-氯-5-(三氟甲基)-3-吡啶羧酸甲酯+

78686-77-85-溴-6-氯烟酸甲酯

参考文献

Mulder, Jason A.; Frutos, Rogelio P.; Patel, Nitinchandra D.; Qu, Bo; Sun, Xiufeng; Tampone, Thomas G.; Gao, Joe; Sarvestani, Max; Eriksson, Magnus C.; Haddad, Nizar; Shen, Sherry; Song, Jinhua J.; Senanayake, Chris H.
Organic Process Research and Development, 2013 , vol. 17, # 6 p. 940 - 945

5006-66-66-羟基烟酸

73781-91-66-氯烟酸甲酯+

1360952-35-76-氯-5-(三氟甲基)-3-吡啶羧酸甲酯

参考文献

Mulder, Jason A.; Frutos, Rogelio P.; Patel, Nitinchandra D.; Qu, Bo; Sun, Xiufeng; Tampone, Thomas G.; Gao, Joe; Sarvestani, Max; Eriksson, Magnus C.; Haddad, Nizar; Shen, Sherry; Song, Jinhua J.; Senanayake, Chris H.
Organic Process Research and Development, 2013 , vol. 17, # 6 p. 940 - 945

5006-66-66-羟基烟酸

222970-61-85-硝基-6-氧代-1,6-二氢-吡啶-3-羧酸甲酯

参考文献

Berrie et al.
Journal of the Chemical Society, 1951 , p. 2590,2593

5006-66-66-羟基烟酸

15871-85-92-甲氧基-5-氰基吡啶

参考文献

Forrest; Walker
Journal of the Chemical Society, 1948 , p. 1939,1942

5006-66-66-羟基烟酸

262295-96-5(6-甲氧基吡啶-3-基)甲基胺

参考文献

Forrest; Walker
Journal of the Chemical Society, 1948 , p. 1939,1942

5006-66-66-羟基烟酸

29241-62-15-溴-6-氯烟酸

参考文献

Roever, Stephan; Andjelkovic, Mirjana; Benardeau, Agnes; Chaput, Evelyne; Guba, Wolfgang; Hebeisen, Paul; Mohr, Susanne; Nettekoven, Matthias; Obst, Ulrike; Richter, Wolfgang F.; Ullmer, Christoph; Waldmeier, Pius; Wright, Matthew B.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 24 p. 9874 - 9896

5006-66-66-羟基烟酸+

64-17-5乙醇

171876-22-56-氯-5-硝基吡啶-3-甲酸乙酯

参考文献

Boehringer Ingelheim (Canada) Ltd.
Patent: US2003/236251 A1, 2003 ;
Location in patent: Page 22 ;