氯甲酸苄酯合成路线

Clausen, Kim; Thorsen, Michael; Lawesson, Sven-Olov; Spatola, Arno F.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 4 p. 785 - 798

6027-21-0D-高丝氨酸+

501-53-1氯甲酸苄酯

41088-85-1Cbz-D-高丝氨酸

参考文献

WO2009/125366 A1, ;

Page/Page column 45 ;

6027-21-0D-高丝氨酸+

501-53-1氯甲酸苄酯

41088-85-1Cbz-D-高丝氨酸+

41088-89-5(R)-2-氧代四氢呋喃-3-基氨基甲酸苄酯

参考文献

Organic Letters, , vol. 1, # 5 p. 803 - 806

501-53-1氯甲酸苄酯

550378-39-7(S)-1-Cbz-3-氨基吡咯烷盐酸盐

参考文献

Hennessy, Edward J.; Saeh, Jamal C.; Sha, Li; MacIntyre, Terry; Wang, Haiyun; Larsen, Nicholas A.; Aquila, Brian M.; Ferguson, Andrew D.; Laing, Naomi M.; Omer, Charles A.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 4 p. 1690 - 1694

2013-12-9正缬氨酸+

501-53-1氯甲酸苄酯

42918-89-8Z-D-正缬氨酸

参考文献

Fraser, Benjamin H.; Mulder, Roger J.; Perlmutter, Patrick
Tetrahedron, 2006 , vol. 62, # 12 p. 2857 - 2867

6027-21-0D-高丝氨酸+

501-53-1氯甲酸苄酯

41088-89-5(R)-2-氧代四氢呋喃-3-基氨基甲酸苄酯

参考文献

King, Amber M.; Salome, Christophe; Dinsmore, Jason; Salome-Grosjean, Elise; De Ryck, Marc; Kaminski, Rafal; Valade, Anne; Kohn, Harold
Journal of Medicinal Chemistry, 2011 , vol. 54, # 13 p. 4815 - 4830