1: With water; silver nitrate in ethanol T=20°C; 2 h; 2: With potassium cyanide in ethanol; water

[Cp*Ru{PhP(C6H4-o-S)2}RuCp*](OTf)2; isopropyl alcohol in 1,2-dichloro-ethane T=60°C; 2 h;

bis(acetylacetonate)nickel(II); triphenylphosphine in tetrahydrofuran T=20°C; Inert atmosphere; regioselective reaction;

1.1: iodine; magnesium / tetrahydrofuran / 2 h / Inert atmosphere; Reflux 1.2: 2 h / Reflux; Inert atmosphere 2.1: silver nitrate / ethanol; water / 2 h / 0 - 20 °C / Darkness View Scheme

1.1: (methoxymethyl)-triphenylphosphonium chloride; potassium tert-butylate / tetrahydrofuran / 12 h / 0 - 20 °C 1.2: 12 h / |Reflux 2.1: triphenylphosphine / dichloromethane / 0.5 h / 0 °C 2.2: 3 h / 0 °C 3.1: tert.-butyl lithium / tetrahydrofuran / -78 - 20 °C View Scheme

1.1: triphenylphosphine / dichloromethane / 0.5 h / 0 °C 1.2: 3 h / 0 °C 2.1: tert.-butyl lithium / tetrahydrofuran / -78 - 20 °C View Scheme