5-溴-2-氟吡啶-3-硼酸合成路线 (共 4 条)
反应条件
1: With lithium diisopropyl amide in tetrahydrofuran; hexane T=-78°C; 0.5 h; 2: With boric acid trimethyl ester in tetrahydrofuran; hexane T=-78 - 20°C; 1 h; 3: With sodium hydrogencarbonate in tetrahydrofuran; hexane
参考文献
Sutherland, Andrew; Gallagher, Timothy
Journal of Organic Chemistry, 2003 , vol. 68, # 8 p. 3352 - 3355
反应条件
dihydrogen peroxide; acetic acid in ethanol; water; ethyl acetate T=35°C; 3 h;
参考文献
Barberousse, Veronique; Bondoux, Michel; Thomas, Didier; Peyrou, Vincent
Patent: US2008/293768 A1, 2008 ;
Location in patent: Page/Page column 7 ;
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethanol; water; toluene Suzuki coupling; 6 h; Heating;
参考文献
Sutherland, Andrew; Gallagher, Timothy
Journal of Organic Chemistry, 2003 , vol. 68, # 8 p. 3352 - 3355
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethanol; water; toluene Suzuki coupling; 6 h; Heating;
参考文献
Sutherland, Andrew; Gallagher, Timothy
Journal of Organic Chemistry, 2003 , vol. 68, # 8 p. 3352 - 3355