3,7,11-三甲基-1,3,6,10-十二碳-四烯合成路线 （共 28 条）
反应条件
1: 1.) n-BuLi / 1.) THF, pentane, RT, 2.) THF, pentane, -78 deg C, 15 min 2: 93 percent / xylene / 0.08 h / Heating View Scheme
参考文献
Fielder; Rowan
Journal of Labelled Compounds and Radiopharmaceuticals, 1994 , vol. 34, # 11 p. 1075 - 1085
反应条件
(i) PBr3, CuBr, Et2O, (ii) Zn; Multistep reaction;
参考文献
Yasuda,A. et al.
Bulletin of the Chemical Society of Japan, 1979 , vol. 52, p. 1752 - 1756
反应条件
1: 42 percent / periodic acid / tetrahydrofuran / 0.03 h / Ambient temperature 2: 1.) n-BuLi / 1.) THF, pentane, RT, 2.) THF, pentane, -78 deg C, 15 min View Scheme
参考文献
Fielder; Rowan
Journal of Labelled Compounds and Radiopharmaceuticals, 1994 , vol. 34, # 11 p. 1075 - 1085
反应条件
1: 73 percent / periodic acid / tetrahydrofuran / 0.03 h / Ambient temperature 2: 78.3 percent / xylene / 0.08 h / Heating 3: 1.) n-BuLi / 1.) THF, pentane, RT, 2.) THF, pentane, -78 deg C, 15 min View Scheme
参考文献
Fielder; Rowan
Journal of Labelled Compounds and Radiopharmaceuticals, 1994 , vol. 34, # 11 p. 1075 - 1085
反应条件
1: 1.) BuLi 2: 83 percent / xylene / Heating View Scheme
参考文献
Spicer, Julie A.; Brimble, Margaret A.; Rowan, Daryl D.
Australian Journal of Chemistry, 1993 , vol. 46, # 12 p. 1929 - 1940
反应条件
1: TsOH / acetone; H2O / 4 h / Ambient temperature 2: (i) NaH, diglyme, (ii) /BRN= 2238274/ 3: LiAlH4 / diethyl ether / 2 h / Ambient temperature 4: MnO2 / petroleum ether / 8 h 5: dimethylsulfoxide / 3 h / 40 °C View Scheme
参考文献
Vig,O.P.; Anand,R.C.
Journal of the Indian Chemical Society, 1970 , vol. 47, p. 851 - 854
反应条件
1: (i) NaH, diglyme, (ii) /BRN= 2238274/ 2: LiAlH4 / diethyl ether / 2 h / Ambient temperature 3: MnO2 / petroleum ether / 8 h 4: dimethylsulfoxide / 3 h / 40 °C View Scheme
参考文献
Vig,O.P.; Anand,R.C.
Journal of the Indian Chemical Society, 1970 , vol. 47, p. 851 - 854
反应条件
1: MnO2 / petroleum ether / 8 h 2: dimethylsulfoxide / 3 h / 40 °C View Scheme
参考文献
Vig,O.P.; Anand,R.C.
Journal of the Indian Chemical Society, 1970 , vol. 47, p. 851 - 854
反应条件
potassium hydrogensulfate
参考文献
Brieger,G. et al.
Journal of Organic Chemistry, 1969 , vol. 34, p. 3789 - 3791
反应条件
in dimethyl sulfoxide T=40°C; 3 h;
参考文献
Vig,O.P.; Anand,R.C.
Journal of the Indian Chemical Society, 1970 , vol. 47, p. 851 - 854
