2-(3-甲氧基苯基)乙醇合成路线 （共 48 条）
反应条件
AlCl3, aluminium chloride in dichloromethane
T=0°C; 1 h;
参考文献
Pfizer Inc., Pfizer Inc.
Patent: US2004/77853 A1, 2004 ;
Location in patent: Page 47;48 ;
反应条件
hydrogenchloride in sodium hydroxide; dichloromethane
参考文献
Pfizer Inc
Patent: US6486325 B1, 2002 ;
反应条件
aluminum tri-bromide in dichloromethane
T=0 - 15°C; 1.75 h;
参考文献
Caron, Stephane; Do, Nga M.; Sieser, Janice E.; Arpin, Patrice; Vazquez, Enrique
Organic Process Research and Development, 2007 , vol. 11, # 6 p. 1015 - 1024
反应条件
1: 83 percent / triphenylphosphine; diethyl azodicarboxylate / tetrahydrofuran / 25 h / 20 °C
2: 89 percent / hydrazine / ethanol / 1 h / Heating
View Scheme
参考文献
Pegurier, Cecile; Morellato, Laurence; Chahed, Eminn; Andrieux, Jean; Nicolas, Jean-Paul; Boutin, Jean A.; Bennejean, Caroline; Delagrange, Philippe; Langlois, Michel
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 5 p. 789 - 800
反应条件
Multistep reaction.;
参考文献
Arisawa; Ramesh; Nakajima; Tohma; Kita
Journal of Organic Chemistry, 2001 , vol. 66, # 1 p. 59 - 65
反应条件
1: tetrachloromethane; PBr3
2: ethanol; sodium ethylate
View Scheme
参考文献
Hewett
Journal of the Chemical Society, 1936 , p. 50
反应条件
hydrogen bromide; tri-n-butylhexadecylphosphonium bromide
Substitution; demethylation; 1.5 h; Heating;
参考文献
Hashima, Hirofumi; Hayashi, Masahiko; Kamano, Yoshiaki; Sato, Nobuhiro
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 7 p. 1757 - 1766
反应条件
hydrogen bromide
Heating;
参考文献
Moreau,C.; Rouessac,F.
Bulletin de la Societe Chimique de France, 1973 , p. 3427 - 3432
