(S)-1-苄基-3-异丁基哌嗪-2,5-二酮合成路线 （共 4 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=20°C; Reflux;
参考文献
Organic Letters, , vol. 10, # 7 p. 1473 - 1476
反应条件
1: With dicyclohexyl-carbodiimide in dichloromethane
T=0 - 25°C; 3.25 h;
2: With hydrogenchloride in dichloromethane
4 h;
参考文献
SCHERING CORPORATION
Patent: US2004/138226 A1, 2004 ;
Location in patent: Page 16 ;
反应条件
hydrogenchloride in dichloromethane
4 h;
参考文献
Schering Corporation
Patent: US2003/232837 A1, 2003 ;
Location in patent: Page 16 ;
反应条件
triethylamine in methanol
20 h; Reflux;
参考文献
Maity, Prantik; Koenig, Burkhard
Organic Letters, 2008 , vol. 10, # 7 p. 1473 - 1476
