1-N-Boc-4-N-苄基-2-乙基哌嗪合成路线 （共 3 条）
反应条件
hydrogen; palladium on activated charcoal in methanol 16 h;
参考文献
Journal of Medicinal Chemistry, , vol. 39, # 7 p. 1345 - 1348
反应条件
in dichloromethane
2 h;
参考文献
Williams; Ciccarone; MacTough; Bock; Conner; Davide; Hamilton; Koblan; Kohl; Kral; Mosser; Omer; Pompliano; Rands; Schaber; Shah; Wilson; Gibbs; Graham; et al.
Journal of Medicinal Chemistry, 1996 , vol. 39, # 7 p. 1345 - 1348
反应条件
1: DCC / CH2Cl2 / 18 h
2: 1.) aq. HCl, 2.) aq. NaHCO3 / 1.) CHCl3
3: LiAlH4 / tetrahydrofuran / 15 h / Heating
4: CH2Cl2 / 2 h
View Scheme
参考文献
Williams; Ciccarone; MacTough; Bock; Conner; Davide; Hamilton; Koblan; Kohl; Kral; Mosser; Omer; Pompliano; Rands; Schaber; Shah; Wilson; Gibbs; Graham; et al.
Journal of Medicinal Chemistry, 1996 , vol. 39, # 7 p. 1345 - 1348
