4-(2-羟基乙基)-2-吡啶羧酸合成路线 （共 2 条）
反应条件
1: 2,6-lutidine / CH2Cl2 / 0.17 h / 0 °C
2: aq. H2O2; MeReO3 / CH2Cl2 / 1 h / 20 °C
3: dimethylcarbamoyl chloride / CH2Cl2 / 23 h / 20 °C
4: 6 N aq. HCl / 24 h / Heating
View Scheme
参考文献
Simeone, Joseph P; Bugianesi, Robert L; Ponpipom, Mitree M; Yang, Yi Tien; Lo, Jane-Ling; Yudkovitz, Joel B; Cui, Jisong; Mount, George R; Ren, Rena Ning; Creighton, Mellissa; Mao, An-Hua; Vincent, Stella H; Cheng, Kang; Goulet, Mark T
Bioorganic and medicinal chemistry letters, 2002 , vol. 12, # 22 p. 3329 - 3332
反应条件
hydrogenchloride
24 h; Heating;
参考文献
Simeone, Joseph P; Bugianesi, Robert L; Ponpipom, Mitree M; Yang, Yi Tien; Lo, Jane-Ling; Yudkovitz, Joel B; Cui, Jisong; Mount, George R; Ren, Rena Ning; Creighton, Mellissa; Mao, An-Hua; Vincent, Stella H; Cheng, Kang; Goulet, Mark T
Bioorganic and medicinal chemistry letters, 2002 , vol. 12, # 22 p. 3329 - 3332
