5,6,7,8-四氢异喹啉-5-胺合成路线 （共 4 条）
反应条件
hydrogen; palladium 10 on activated carbon in ethanol; ethyl acetate
P=3102.97 Torr; 10 h;
参考文献
Gruenenthal GmbH
Patent: US2012/115893 A1, 2012 ;
Location in patent: Page/Page column 32 ;
US 20120115893 A1
反应条件
hydrogen; palladium 10 on activated carbon in ethanol; ethyl acetate
20 h;
参考文献
Merck Sharp and Dohme Limited
Patent: WO2004/46133 A1, 2004 ;
Location in patent: Page 24 ;
WO 2004/046133 A1
反应条件
1.1: hydrogen; trifluoroacetic acid / palladium 10 on activated carbon / 65 °C / 3878.71 Torr
2.1: potassium tert-butylate / tetrahydrofuran / 12 h / 20 °C
2.2: 0 - 20 °C
3.1: hydrogen / palladium 10 on activated carbon / ethyl acetate; ethanol / 10 h / 3102.97 Torr
View Scheme
参考文献
GRUeNENTHAL GMBH; FRANK, Robert; CHRISTOPH, Thomas; FRORMANN, Sven
Patent: WO2012/62463 A1, 2012 ;
反应条件
1.1: potassium tert-butylate / tetrahydrofuran / 12 h / 20 °C
1.2: 0 - 20 °C
2.1: hydrogen / palladium 10 on activated carbon / ethyl acetate; ethanol / 10 h / 3102.97 Torr
View Scheme
参考文献
GRUeNENTHAL GMBH; FRANK, Robert; CHRISTOPH, Thomas; FRORMANN, Sven
Patent: WO2012/62463 A1, 2012 ;
