3-(3-噻吩)-2-丙酸乙酯合成路线 （共 5 条）
反应条件
potassium hydroxide 4 h; Heating;
参考文献
Chemistry - A European Journal, , vol. 12, # 10 p. 2739 - 2744
反应条件
1: With diisobutylaluminium hydride in dichloromethane
T=0°C; 0.5 h;
2: With hydrogenchloride; water
参考文献
Osaka University; KOBAYASHI, Motomasa; KOTOKU, Naoyuki; ARAI, Masayoshi; KAWACHI, Takashi
Patent: EP2567956 A1, 2013 ;
Location in patent: Paragraph 0046 ;
反应条件
hydrogen; palladium on activated charcoal in ethanol
120 h;
参考文献
Moustrou, Corinne; Samat, Andre; Guglielmetti, Robert; Dubest, Roger; Garnier, Francis
Helvetica Chimica Acta, 1995 , vol. 78, p. 1887 - 1893
反应条件
1: 80 percent / H2 / 10percent Pd/BaSO4 / methanol / 2 h
2: DIBAH / toluene / 4 h / -70 °C
3: 1.) n-BuLi / 1.) THF, hexane, -30 deg C, 45 min, 2.) THF, -30 to -10 deg C, 90 min
View Scheme
参考文献
Weyerstahl, Peter; Schenk, Anja; Marschall, Helga
Liebigs Annalen, 1995 , # 10 p. 1849 - 1854
反应条件
1: 80 percent / H2 / 10percent Pd/BaSO4 / methanol / 2 h
2: DIBAH / toluene / 4 h / -70 °C
View Scheme
参考文献
Osaka University; KOBAYASHI, Motomasa; KOTOKU, Naoyuki; ARAI, Masayoshi; KAWACHI, Takashi
Patent: EP2567956 A1, 2013 ;
