1: 2,3-Difluoro-phenol With magnesium methanolate in toluene
0.666667 h; Reflux;
2: formaldehyd in toluene
T=115°C; 0.783333 h;
3: With hydrogenchloride; water in toluene
T=20°C;
参考文献
NSAB, FILIAL AF NEUROSEARCH SWEDEN AB, SVERIGE
Patent: WO2009/133109 A1, 2009 ;
Location in patent: Page/Page column 49 ;