N,N-二甲基-3-硝基吡啶-2-胺合成路线 （共 8 条）
反应条件
sodium hydride in N,N-dimethyl-formamide T=100°C;
参考文献
Locus Pharmaceuticals, Inc.
Patent: US2008/280891 A1, 2008 ;
Location in patent: Page/Page column 53 ;
反应条件
15 h; Refluxneat (no solvent);
参考文献
Kodimuthali, Arumugam; Mungara, Anitha; Prasunamba, Padala Lakshmi; Pal, Manojit
Journal of the Brazilian Chemical Society, 2010 , vol. 21, # 8 p. 1439 - 1445
参考文献
Pharmacia and Upjohn Company
Patent: US5668157 A1, 1997 ;
US 5668157 A
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate T=115 - 120°C; Suzuki-Miyaura coupling; 17 h;
参考文献
Gray; Andrews; Hook; Kitteringham; Voyle
Tetrahedron Letters, 2000 , vol. 41, # 32 p. 6237 - 6240
反应条件
70 h; Refluxneat (no solvent);
参考文献
Kodimuthali, Arumugam; Mungara, Anitha; Prasunamba, Padala Lakshmi; Pal, Manojit
Journal of the Brazilian Chemical Society, 2010 , vol. 21, # 8 p. 1439 - 1445
反应条件
sulfuric acid; nitric acid
参考文献
Tschitschibabin; Knunjanz
Chemische Berichte, 1928 , vol. 61, p. 430
Chemische Berichte, 1929 , vol. 62, p. 3053
反应条件
hydrogen; palladium 10 on activated carbon in methanol; ethyl acetate
P=2585.81 Torr;
参考文献
LOCUS PHARMACEUTICALS, INC.
Patent: WO2008/8059 A1, 2008 ;
Location in patent: Page/Page column 156 ;
反应条件
sodium hydrogencarbonate in ethanol
参考文献
Pharmacia and Upjohn Company
Patent: US5668157 A1, 1997 ;
US 5668157 A
