反应条件
1: 89 percent / thionyl chloride / diethyl ether / 16 h / Ambient temperature
2: pyridine / diethyl ether / 10 h / Ambient temperature
3: 2.) triphenylphosphine, 2,2'-dithiodipyridine / 1.) chloroform, RT, 12 h, 2.) chloroform, 8 h, reflux, 12 h
4: 57 percent / triethylamine, (4-dimethylamino)pyridine / CH2Cl2 / 96 h / Ambient temperature
5: hydrogen / platinum oxide / acetic acid
6: 1.) 1M-diborane, 2.) barium hydroxide / 1.) THF, 0 deg C, 5 min, 2.) THF, RT, 1 h, 3.) water, RT, 12 h
View Scheme
参考文献
Brown, Kenneth; Devlin, J. Alastair; Robins, David J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 8 p. 1819 - 1824
