1-氯-3-甲基-2-丁烯合成路线 （共 287 条）
反应条件
[Pt(dba)2]; triphenyl-arsane; triethylamine in toluene T=50°C; borylation; 16 h;
参考文献
Murata, Miki; Watanabe, Shinji; Masuda, Yuzuru
Tetrahedron Letters, 2000 , vol. 41, # 31 p. 5877 - 5880
反应条件
sodium hydroxide; tetra-(n-butyl)ammonium iodide in toluene T=80°C; 4.5 h;
参考文献
Mayr, Herbert; Heilmann, Werner; Baeuml, Engelbert; Vorbrueggen, Helmut
Chemische Berichte, 1991 , vol. 124, # 1 p. 203 - 206
参考文献
Akhnazaryan,A.A. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1964 , vol. 34, # 5 p. 1413 - 1419,1417 - 1422
反应条件
1: (i) NaOEt, EtOH, (ii) /BRN= 878156/ 2: (i) NaOEt, EtOH, (ii) /BRN= 969135/ View Scheme
参考文献
Julia,S.; Linstrumelle,G.
Bulletin de la Societe Chimique de France, 1966 , p. 3490 - 3498
反应条件
cesium fluoride; tris-(dibenzylideneacetone)dipalladium(0) in acetonitrile T=80°C; Elimination; Cyclization; 3 h;
参考文献
Yoshikawa, Eiji; Yamamoto, Yoshinori
Angewandte Chemie - International Edition, 2000 , vol. 39, # 1 p. 173 - 175
反应条件
cesium fluoride; 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0) in tetrahydrofuran; acetonitrile T=60°C; Elimination; Cyclization; 24 h; Title compound not separated from byproducts;
参考文献
Yoshikawa, Eiji; Radhakrishnan; Yamamoto, Yoshinori
Journal of the American Chemical Society, 2000 , vol. 122, # 30 p. 7280 - 7286
反应条件
1: (i) NaOEt, EtOH, (ii) /BRN= 878156/ 2: (i) KOH, EtOH, H2O, (ii) Cu, quinoline, (heating) 3: (COCl)2 / petroleum ether 4: diethyl ether View Scheme
参考文献
Julia,S.; Linstrumelle,G.
Bulletin de la Societe Chimique de France, 1966 , p. 3490 - 3498
反应条件
1: 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical With naphthalene; sodium in tetrahydrofuran T=20°C; 2: 1-chloro-3-methyl-2-butene in tetrahydrofuran 24 h; Heating;
参考文献
Inokuchi, Tsutomu; Kawafuchi, Hiroyuki
Tetrahedron, 2004 , vol. 60, # 51 p. 11969 - 11975
反应条件
sodium 1.) ether, 1 h, 2.) ether, reflux, 30 min; Yield given. Multistep reaction;
参考文献
Yamada, Shigetoshi; Takeshita, Toru; Tanaka, Juntaro
Bulletin of the Chemical Society of Japan, 1986 , vol. 59, # 9 p. 2901 - 2902
反应条件
potassium hydroxide T=0°C; 1.5 h;
参考文献
Crombie, Leslie; Jones, Raymond C. F.; Palmer, Christopher J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 317 - 332
