1-氯-3-甲基-2-丁烯合成路线 （共 287 条）
反应条件
1.1: 96.4 percent / TEBA / 4.5 h / 95 - 105 °C
2.1: 95 percent / aq. NaOH / 2.5 h / 100 °C
3.1: 95 percent / MnO2 / petroleum ether / 7 h / 20 °C
4.1: LiCl; hydroquinone / toluene / Heating
4.2: LiCl / various solvent(s) / 135 °C
View Scheme
参考文献
Vani; Chida; Srinivasan; Chandrasekharam; Singh
Synthetic Communications, 2001 , vol. 31, # 2 p. 219 - 224
反应条件
ethanol; sodium
Substitution; 3.5 h; Heating;
参考文献
Bach, Thorsten; Koerber, Christina
Journal of Organic Chemistry, 2000 , vol. 65, # 8 p. 2358 - 2367
反应条件
in diethyl ether
48 h;
参考文献
Detty, Michael R.; Wood, Gary P.
Journal of Organic Chemistry, 1980 , vol. 45, # 1 p. 80 - 89
参考文献
de la Mare; Vernon
Journal of the Chemical Society, 1953 , p. 3555,3557
参考文献
Nasarow et al.
Zhurnal Obshchei Khimii, 1952 , vol. 22, p. 611,614; engl. Ausg. S. 671, 673
反应条件
potassium hydroxide
T=0°C; 1.5 h;
参考文献
Crombie, Leslie; Jones, Raymond C. F.; Palmer, Christopher J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 317 - 332
反应条件
in tetrahydrofuran
24 h;
参考文献
Matsushita,H.; Negishi,E.I.
Journal of the American Chemical Society, 1981 , vol. 103, p. 2882
反应条件
magnesium in tetrahydrofuran
Ambient temperature;
参考文献
Dubac, J.; Laporterie, A.; Iloughmane, H.; Pillot, J. P.; Deleris, G.; Dunogues, J.
Journal of Organometallic Chemistry, 1985 , vol. 281, p. 149 - 162
反应条件
in tetrahydrofuran
T=-70 - 20°C;
参考文献
Negishi, Ei-ichi; Luo, Fen-Tair; Rand, Cynthia L.
Tetrahedron Letters, 1982 , vol. 23, p. 27 - 30
反应条件
in dichloromethane
T=50°C; P=7500600 Torr; 48 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Yamamoto, Yoshinori; Maruyama, Kazuhiro; Matsumoto, Kiyoshi
Tetrahedron Letters, 1984 , vol. 25, # 10 p. 1075 - 1078
