1-氯-3-甲基-2-丁烯合成路线 （共 287 条）
反应条件
sodium azide in water; acetone
参考文献
Gagneux,A. et al.
Journal of the American Chemical Society, 1960 , vol. 82, p. 5956 - 5957
反应条件
sodium azide in pentane
参考文献
Deslongchamps,P. et al.
Canadian Journal of Chemistry, 1979 , vol. 57, p. 3262 - 3271
反应条件
1: 22 percent / NaBH4 / ethanol / 2 h / 20 °C
2: 41 percent / benzene / 2 h / 100 °C / Photolysis
View Scheme
参考文献
Yamago, Shigeru; Hashidume, Masahiro; Yoshida, Jun-Ichi
Tetrahedron, 2002 , vol. 58, # 34 p. 6805 - 6813
反应条件
titanium tetrachloride in dichloromethane
T=-78°C; 3 h;
参考文献
Hosomi, Akira; Imai, Takafumi; Endo, Masahiko; Sakurai, Hideki
Journal of Organometallic Chemistry, 1985 , vol. 285, p. 95 - 108
参考文献
Henne; Chanan
Journal of the American Chemical Society, 1944 , vol. 66, p. 393
参考文献
Descoins,C. et al.
Bulletin de la Societe Chimique de France, 1971 , p. 4087 - 4093
反应条件
1: 67 percent / tetrahydrofuran / 1.) 10-15 deg C, 2 h; 2.) r.t.;
2: 1.) magnesium, 1,2-dibromoethane, iodine; 2.) NiCl2 / 1.) THF, 100-110 deg C, 2 h; 2.) THF r.t., 4.5 h
3: 93 percent / NaOH / ethanol; H2O / 6 h / Ambient temperature
View Scheme
参考文献
Amano; Yoshikawa; Ogawa; Sano; Ohuchi; Tanami; Ota; Hatayama; Higuchi; Amanuma
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 11 p. 4653 - 4662
反应条件
sodium hydroxide; tetrabutylammomium bromide in water
参考文献
Haarmann and Reimer GmbH
Patent: US6252120 B1, 2001 ;
参考文献
Reetz,M.T. et al.
Tetrahedron Letters, 1979 , p. 4971 - 4974
反应条件
magnesium
1.) ether, 0-5 deg C, 1.5 h; 2.) ether, 20 deg C, 3 h; Yield given. Multistep reaction;
参考文献
Laduranty, Joelle; Barbot, Francis; Miginiac, Leone
Bulletin de la Societe Chimique de France, 1989 , # 6 p. 850 - 855
