1-氯-3-甲基-2-丁烯合成路线 （共 287 条）
参考文献
Martin,M.M.; Gleicher,G.J.
Journal of the American Chemical Society, 1964 , vol. 86, p. 238 - 241
参考文献
Muir,D.M.; Parker,A.J.
Journal of Organic Chemistry, 1976 , vol. 41, p. 3201 - 3204
参考文献
Bernotas, Ronald C.; Adams, Ginette; Carr, Albert A.
Tetrahedron, 1996 , vol. 52, # 19 p. 6519 - 6526
反应条件
potassium hydroxide
T=0°C; 1.5 h;
参考文献
Crombie, Leslie; Jones, Raymond C. F.; Palmer, Christopher J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 317 - 332
反应条件
sodium cyanide in N,N-dimethyl-formamide
T=50°C; 2 h;
参考文献
Cane, David E.; Yang, Guohan; Coates, Robert M.; Pyun, Hyung-Jung; Hohn, Thomas M.
Journal of Organic Chemistry, 1992 , vol. 57, # 12 p. 3454 - 3462
反应条件
in N,N-dimethyl-formamide
T=0 - 30°C;
参考文献
Smith, Sean M.; Thacker, Nathan C.; Takacs, James M.
Journal of the American Chemical Society, 2008 , vol. 130, # 12 p. 3734 - 3735
反应条件
potassium iodide in benzene
参考文献
Katagiri,T. et al.
Bulletin of the Chemical Society of Japan, 1976 , vol. 49, p. 3715 - 3716
参考文献
Alkaloida Vegyeszeti Gyar
Patent: US4716238 A1, 1987 ;
反应条件
1: palladium dichloride; potassium acetate / tetrahydrofuran / 12 h / 60 °C / |Inert atmosphere
2: potassium phosphate; C26H39P; bis(η3-allyl-μ-chloropalladium(II)) / acetonitrile; water / 12 h / 70 °C / |Inert atmosphere
View Scheme
参考文献
Yang, Yang; Buchwald, Stephen L.
Journal of the American Chemical Society, 2013 , vol. 135, # 29 p. 10642 - 10645
反应条件
potassium carbonate; 1-n-butyl-3-methylimidazolium hexafluorophosphate
T=90°C; 5 h;
参考文献
Kryshtal; Zhdankina; Zlotin
Russian Chemical Bulletin, 2004 , vol. 53, # 3 p. 652 - 658
