2-丁基-1,6-二氢-4-甲基-6-氧代-1-[[2'-[1-(三苯甲基)-1H-四氮唑-5-基][1,1'-联苯]-4-基]甲基]-5-嘧啶乙酸乙酯合成路线 (共 2 条)
反应条件
1: water; sodium hydroxide / methanol / 20 °C 2: 4-methyl-morpholine; benzotriazol-1-ol; dicyclohexyl-carbodiimide / chloroform 3: Lawesson's reagent / toluene / Reflux 4: hydrogenchloride; water / methanol / Reflux View Scheme
参考文献
Kim, Tae Woo; Yoo, Byoung Wook; Lee, Joon Kwang; Kim, Ji Han; Lee, Kyung-Tae; Chi, Yong Ha; Lee, Jae Yeol
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 4 p. 1649 - 1654
反应条件
1: water; sodium hydroxide / methanol / 20 °C
2: 4-methyl-morpholine; benzotriazol-1-ol; dicyclohexyl-carbodiimide / chloroform
View Scheme
参考文献
Kim, Tae Woo; Yoo, Byoung Wook; Lee, Joon Kwang; Kim, Ji Han; Lee, Kyung-Tae; Chi, Yong Ha; Lee, Jae Yeol
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 4 p. 1649 - 1654