4-氧代-4,5-二氢-3H-吡咯并[2,3-c]喹啉-1-甲腈合成路线 （共 6 条）
参考文献
Pierre Fabre Medicament
Patent: US2009/42876 A1, 2009 ;
Location in patent: Page/Page column 22 ;
反应条件
iron; acetic acid
0.666667 h; Heating;
参考文献
Bergman, Jan; Rehn, Stanley
Tetrahedron, 2002 , vol. 58, # 45 p. 9179 - 9185
反应条件
1: 66 percent / piperidine / ethanol / 1.5 h / Heating
2: 72 percent / DBU / tetrahydrofuran / 0 - 20 °C
3: 65 percent / Fe; AcOH / 0.67 h / Heating
View Scheme
参考文献
Bergman, Jan; Rehn, Stanley
Tetrahedron, 2002 , vol. 58, # 45 p. 9179 - 9185
反应条件
1: With PPA
T=130°C; 2 h;
2: With water
T=0°C; 0.5 h;
参考文献
Pierre Fabre Medicament
Patent: US2009/42876 A1, 2009 ;
Location in patent: Page/Page column 22 ;
反应条件
1: With PPA
T=130°C; 2 h;
2: With water
T=0°C; 0.5 h;
参考文献
Pierre Fabre Medicament
Patent: US2009/42876 A1, 2009 ;
Location in patent: Page/Page column 22 ;
反应条件
sulfuric acid
3.66667 h; Heating;
参考文献
Bergman, Jan; Rehn, Stanley
Tetrahedron, 2002 , vol. 58, # 45 p. 9179 - 9185
