4-羟基-4-(4-甲氧基苯基)哌啶合成路线 （共 4 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol
P=2844.31 Torr; 2 h;
参考文献
Lyles-Eggleston; Margaret; McCollough; Craig; Fan; Pingchen; Ablordeppey; Mardenborough, Joy H.; Leroy; Seth; Borne
Medicinal Chemistry Research, 1999 , vol. 9, # 9 p. 686 - 695
反应条件
1.1: Mg / tetrahydrofuran / 5 h / Heating
1.2: 7 percent / tetrahydrofuran / 24 h / Heating
2.1: H2 / 10 percent Pd/C / ethanol / 2 h / 2844.31 Torr
View Scheme
参考文献
Lyles-Eggleston; Margaret; McCollough; Craig; Fan; Pingchen; Ablordeppey; Mardenborough, Joy H.; Leroy; Seth; Borne
Medicinal Chemistry Research, 1999 , vol. 9, # 9 p. 686 - 695
反应条件
1.1: Mg / tetrahydrofuran / 5 h / Heating
1.2: 7 percent / tetrahydrofuran / 24 h / Heating
2.1: H2 / 10 percent Pd/C / ethanol / 2 h / 2844.31 Torr
View Scheme
参考文献
Lyles-Eggleston; Margaret; McCollough; Craig; Fan; Pingchen; Ablordeppey; Mardenborough, Joy H.; Leroy; Seth; Borne
Medicinal Chemistry Research, 1999 , vol. 9, # 9 p. 686 - 695
反应条件
4-(N,N-dimethlyamino)pyridine; tert-butyldimethylsilyl chloride; triethylamine
T=45°C;
参考文献
Djuric, Stevan W.
Journal of Organic Chemistry, 1984 , vol. 49, # 7 p. 1311 - 1312
