4-甲酰基-2-甲基苯甲酸合成路线 （共 3 条）
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane
T=-78 - 25°C; 2 h;
2: With hydrogenchloride; water in tetrahydrofuran; hexane
参考文献
EXELIXIS, INC.
Patent: WO2009/55077 A1, 2009 ;
Location in patent: Page/Page column 383-384 ;
反应条件
hydrogenchloride; n-butyllithium in tetrahydrofuran; hexane; N,N-dimethyl-formamide
参考文献
Dow AgroSciences LLC; Lo, William C.; Hunter, James E.; Watson, Gerald B.; Patny, Akshay; Iyer, Pravin S.; Boruwa, Joshodeep
Patent: US2014/171312 A1, 2014 ;
Location in patent: Page/Page column ;
反应条件
4-(N,N-dimethlyamino)pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane
T=20°C; 10 h;
参考文献
Bayer CorpScience AG
Patent: US2010/179194 A1, 2010 ;
Location in patent: Page/Page column 26-27 ;
