5-(4-甲氧基苯基)-2-氨基吡啶合成路线 (共 4 条)
反应条件
palladium diacetate; sodium carbonate in water; N,N-dimethyl-formamide T=110°C; Suzuki coupling; 3 h;
参考文献
Journal of Medicinal Chemistry, , vol. 51, # 15 p. 4724 - 4729
反应条件
tripotassium phosphate monohydrate; 4-bromo-benzoic acid ethyl ester; C52H49PRu; bis(dibenzylideneacetone)-palladium(0) in 1,4-dioxane T=100°C; Suzuki-Miyaura Coupling; 4.5 h; Inert atmosphere;
参考文献
Journal of Organic Chemistry, , vol. 78, # 22 p. 11513 - 11524
反应条件
2,2'-azo-bisisobutyronitrile; tris-(trimethylsilyl)silane in acetonitrile; benzene 32 h;
参考文献
Journal of Organic Chemistry, , vol. 73, # 22 p. 8800 - 8807
反应条件
hydrogen bromide
Reflux;
参考文献
Liu, Ping; Zhu, Shaolong; Li, Peng; Xie, Weijie; Jin, Yongsheng; Sun, Qingyan; Wu, Qiuye; Sun, Peng; Zhang, Yingjun; Yang, Xiaohong; Jiang, Yuanying; Zhang, Dazhi
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 11 p. 3261 - 3265