3-硝基-4-(环己基氨基)苯甲酸甲酯合成路线 （共 6 条）
反应条件
in dimethyl sulfoxide
T=60°C; 24 h;
参考文献
GENELABS TECHNOLOGIES, INC.
Patent: WO2004/108687 A2, 2004 ;
Location in patent: Page 22; 30 ;
反应条件
triethylamine in acetonitrile
参考文献
Priestley, Eldon Scott; Decicco, Carl P.; Hudyma, Thomas W.; Zheng, Xiaofan
Patent: US2003/134853 A1, 2003 ;
反应条件
1: sulfuric acid / 0.25 h / 80 °C / |Microwave irradiation; |Inert atmosphere
2: dichloromethane / 0.17 h / 80 °C / |Microwave irradiation; |Inert atmosphere
View Scheme
参考文献
Maiti, Barnali; Chanda, Kaushik; Selvaraju, Manikandan; Tseng, Chih-Chung; Sun, Chung-Ming
ACS Combinatorial Science, 2013 , vol. 15, # 6 p. 291 - 297
反应条件
in dichloromethane
T=80°C; 0.166667 h; Microwave irradiationInert atmosphere;
参考文献
Maiti, Barnali; Chanda, Kaushik; Selvaraju, Manikandan; Tseng, Chih-Chung; Sun, Chung-Ming
ACS Combinatorial Science, 2013 , vol. 15, # 6 p. 291 - 297
反应条件
1: 4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide / dichloromethane / 17 h / 0 - 20 °C / |Inert atmosphere
2: potassium carbonate / dimethyl sulfoxide / 17 h / 60 °C
View Scheme
参考文献
Skouta, Rachid; Dixon, Scott J.; Wang, Jianlin; Dunn, Denise E.; Orman, Marina; Shimada, Kenichi; Rosenberg, Paul A.; Lo, Donald C.; Weinberg, Joel M.; Linkermann, Andreas; Stockwell, Brent R.
Journal of the American Chemical Society, 2014 , vol. 136, # 12 p. 4551 - 4556
反应条件
palladium in methanol; ethyl acetate
参考文献
Priestley, Eldon Scott; Decicco, Carl P.; Hudyma, Thomas W.; Zheng, Xiaofan
Patent: US2003/134853 A1, 2003 ;
