1: 1.) potassium methoxide / 1.) methanol, 5 deg C, 10 min, 2.) reflux, 3.5 h
2: 92 percent / acetic anhydride / 52 h / 25 °C
View Scheme
参考文献
Begley, Michael J.; Mellor, Michael; Pattenden, Gerald
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 8 p. 1905 - 1912
Begley, Michael J.; Mellor, Michael; Pattenden, Gerald
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 8 p. 1905 - 1912
1: 80 percent / toluene-p-sulphonic acid
2: 1.) lithium diisopropylamide, hexamethylphosphoramide / 1.) -78 deg C
3: 83 percent / 20percent sulphuric acid / tetrahydrofuran / 1 h
4: acetic anhydride / 52 h / 25 °C
View Scheme
参考文献
Begley, Michael J.; Mellor, Michael; Pattenden, Gerald
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 8 p. 1905 - 1912
1: 80 percent / toluene-p-sulphonic acid
2: 1.) lithium diisopropylamide, hexamethylphosphoramide / 1.) -78 deg C
3: 83 percent / 20percent sulphuric acid / tetrahydrofuran / 1 h
4: acetic anhydride / 52 h / 25 °C
View Scheme
参考文献
Begley, Michael J.; Mellor, Michael; Pattenden, Gerald
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 8 p. 1905 - 1912
1: 88 percent / DBU / acetonitrile
2: 75 percent / AlCl3 / 1,2-dichloro-ethane / 1 h / -8 °C
3: 100 percent / NaBH4, pyridine / 3 h / Ambient temperature
4: 77 percent / o-chloranil / dioxane / 5 h / Heating
View Scheme
参考文献
Gabbutt, Christopher D.; Hepworth, John D.; Urquhart, Michael W.J.; Vazquez De Miguel, Luis Millan
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 12 p. 1819 - 1824
1: ethyl acetoacetate With acetic acid; sodium nitrite
3 h;
2: 1,3-cylohexanedione With sodium acetate; zinc in acetic acid
Knorr pyrrole synthesis; 1 h;
参考文献
Elliott, Luke D.; Berry, Malcolm; Orr-Ewing, Andrew J.; Booker-Milburn, Kevin I.
Journal of the American Chemical Society, 2007 , vol. 129, # 11 p. 3078 - 3079
