4-羟基-5,6-二甲基吡喃-2-酮合成路线 （共 9 条）
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in benzene 1 h; RefluxInert atmosphere;
参考文献
Oguchi, Takamasa; Watanabe, Kazuhiro; Ohkubo, Koichi; Abe, Hideki; Katoh, Tadashi
Chemistry - A European Journal, 2009 , vol. 15, # 12 p. 2826 - 2845
反应条件
1: NaNH2, NH3 / diethyl ether 2: (im)2CO / tetrahydrofuran View Scheme
参考文献
Schreiber; Satake
Journal of the American Chemical Society, 1984 , vol. 106, # 15 p. 4186 - 4188
反应条件
1: K2CO3 / acetone 2: NaNH2, NH3 / diethyl ether 3: (im)2CO / tetrahydrofuran View Scheme
参考文献
Schreiber; Satake
Journal of the American Chemical Society, 1984 , vol. 106, # 15 p. 4186 - 4188
反应条件
1: With recombinant CazF expressed from S. cerevisiae BJ5464-NpgA2 in aq. phosphate buffer T=20°C; Claisen Condensation; pH=7.4; 1 h; Enzymatic reaction; 2: With sodium hydroxide in water T=65°C; 0.166667 h;
参考文献
Winter, Jaclyn M.; Chiou, Grace; Bothwell, Ian R.; Xu, Wei; Garg, Neil K.; Luo, Minkui; Tang, Yi
Organic Letters, 2013 , vol. 15, # 14 p. 3774 - 3777
反应条件
1: 51 percent / NaH; n-BuLi 2: 68 percent / Jones reagent 3: 54 percent / DBU / benzene View Scheme
参考文献
Hagiwara, Hisahiro; Fujimoto, Norikazu; Suzuki, Toshio; Ando, Masayoshi
Heterocycles, 2000 , vol. 53, # 3 p. 549 - 552
反应条件
1: 68 percent / Jones reagent 2: 54 percent / DBU / benzene View Scheme
参考文献
Hagiwara, Hisahiro; Fujimoto, Norikazu; Suzuki, Toshio; Ando, Masayoshi
Heterocycles, 2000 , vol. 53, # 3 p. 549 - 552
反应条件
2: N,N'-carbonyldiimidazole (CDI) / diethyl ether / 2 h / 0 °C View Scheme
参考文献
Cervello, Jordi; Marquet, Jorge; Moreno-Manas, Marcial
Synthetic Communications, 1990 , vol. 20, # 13 p. 1931 - 1941
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene
T=20°C; 15 h;
参考文献
Hagiwara, Hisahiro; Fujimoto, Norikazu; Suzuki, Toshio; Ando, Masayoshi
Heterocycles, 2000 , vol. 53, # 3 p. 549 - 552
参考文献
Patel, Prakash; Pattenden, Gerald
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 8 p. 1941 - 1945
