4-甲基-2-硝基-苯甲酰氯合成路线 （共 6 条）
反应条件
1: ammonium hydroxide / tetrahydrofuran / 4 h / 0 - 26 °C 2: iron; ammonium chloride / ethanol; water / 2 h / |Reflux View Scheme
参考文献
Glenmark Pharmaceuticals S.A.; GHARAT, Laxmikant Atmaram; Banerjee, Abhisek; Khairatkar-Joshi, Neelima; Kattige, Vidya Ganapati
Patent: US2013/210844 A1, 2013 ;
反应条件
1: CHCl3 / 1 h / Heating 2: stannous chloride / HCl / 24 h 3: 5 h / Heating View Scheme
参考文献
Plescia; Diadone; Raffa; Bajardi; Caruso; Cutuli; Amico-Roxas
Farmaco, 1992 , vol. 47, # 4 p. 465 - 475
反应条件
1: CHCl3 / 1 h / Heating 2: stannous chloride / HCl / 24 h 3: 5 h / Heating View Scheme
参考文献
Plescia; Diadone; Raffa; Bajardi; Caruso; Cutuli; Amico-Roxas
Farmaco, 1992 , vol. 47, # 4 p. 465 - 475
反应条件
1: CHCl3 / 1 h / Heating 2: stannous chloride / HCl / 24 h 3: 5 h / Heating View Scheme
参考文献
Plescia; Diadone; Raffa; Bajardi; Caruso; Cutuli; Amico-Roxas
Farmaco, 1992 , vol. 47, # 4 p. 465 - 475
反应条件
thionyl chloride; N,N-dimethyl-formamide in dichloromethane
T=20°C;
参考文献
Chou, Yuo-Ling; Davey, David D.; Eagen, Keith A.; Griedel, Brian D.; Karanjawala, Rushad; Phillips, Gary B.; Sacchi, Karna L.; Shaw, Kenneth J.; Wu, Shung C.; Lentz, Dao; Liang, Amy M.; Trinh, Lan; Morrissey, Michael M.; Kochanny, Monica J.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 3 p. 507 - 511
反应条件
1: ammonium hydroxide / tetrahydrofuran / 4 h / 0 - 26 °C
2: iron; ammonium chloride / ethanol; water / 2 h / |Reflux
3: 4 h / 110 °C / |Sealed tube
View Scheme
参考文献
Glenmark Pharmaceuticals S.A.; GHARAT, Laxmikant Atmaram; Banerjee, Abhisek; Khairatkar-Joshi, Neelima; Kattige, Vidya Ganapati
Patent: US2013/210844 A1, 2013 ;
