1-(4-甲氧基苯基)-2,5-二甲基吡咯合成路线 （共 9 条）
反应条件
nano lead oxide β-PbO (P85) T=20°C; Paal-Knorr reaction; 1 h; neat (no solvent);
参考文献
Gao, Lanchang; Bing, Liu; Zhang, Zehui; Kecheng, Huang; Xiaoyun, Hu; Deng, Kejian
Journal of Organometallic Chemistry, 2013 , vol. 735, p. 26 - 31
反应条件
indium; acetic acid in toluene T=80°C; 1.5 h; Inert atmosphere;
参考文献
Lee, Hyunseung; Kim, Byeong Hyo
Tetrahedron, 2013 , vol. 69, # 32 p. 6698 - 6708
反应条件
in various solvent(s) T=110°C; pH=3;
参考文献
Zamora, Rosario; Hidalgo, Francisco J.
Synlett, 2006 , # 9 p. 1428 - 1430
反应条件
hydrogenchloride in methanol; water T=20°C; electrolysis; Yields of byproduct given;
参考文献
Concialini, Vittorio; Roffia, Sergio; Savoia, Diego
Gazzetta Chimica Italiana, 1995 , vol. 125, # 2 p. 77 - 82
反应条件
1: hex-3-yne-2,5-diol With ruthenium(II)-carbonyl-tris(triphenylphosphine) dihydride; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in toluene 0.5 h; Inert atmosphereReflux; 2: 4-methoxy-aniline in toluene 23.5 h; Inert atmosphereReflux;
参考文献
Pridmore, Simon J.; Slatford, Paul A.; Taylor, James E.; Whittlesey, Michael K.; Williams, Jonathan M.J.
Tetrahedron, 2009 , vol. 65, # 44 p. 8981 - 8986
反应条件
in various solvent(s) T=110°C; pH=3;
参考文献
Zamora, Rosario; Hidalgo, Francisco J.
Synlett, 2006 , # 9 p. 1428 - 1430
反应条件
9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in toluene 24 h; Heating; Title compound not separated from byproducts.;
参考文献
Pridmore, Simon J.; Slatford, Paul A.; Daniel, Aurelie; Whittlesey, Michael K.; Williams, Jonathan M.J.
Tetrahedron Letters, 2007 , vol. 48, # 29 p. 5115 - 5120
反应条件
hydrogenchloride in ethanol T=120°C; 0.25 h; Microwave irradiation;
参考文献
Walia, Amit; Kang, Soosung; Silverman, Richard B
Journal of Organic Chemistry, 2013 , vol. 78, # 21 p. 10931 - 10937
反应条件
1: N,N-dimethyl-formamide With trichlorophosphate T=20°C; 0.25 h; Inert atmosphere; 2: 1-(4-methoxyphenyl)-2,5-dimethyl-1H-pyrrole T=100°C; Vilsmeier-Haack Formylation; 3 h; Inert atmosphere;
参考文献
Murugesan, Dinakaran; Mital, Alka; Kaiser, Marcel; Shackleford, David M.; Morizzi, Julia; Katneni, Kasiram; Campbell, Michael; Hudson, Alan; Charman, Susan A.; Yeates, Clive; Gilbert, Ian H.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 7 p. 2975 - 2990
