4-(1-吡咯基)苯甲酸乙酯合成路线 （共 9 条）
反应条件
ionic liquid immobilized on γ-Fe2O3(at)SiO2 nanoparticles in water T=100°C; Clauson-Kaas Synthesis; 0.916667 h;
参考文献
Ma, Fei-Ping; Li, Pei-He; Li, Bao-Le; Mo, Li-Ping; Liu, Ning; Kang, Hui-Jun; Liu, Ya-Nan; Zhang, Zhan-Hui
Applied Catalysis A: General, 2013 , vol. 457, p. 34 - 41
反应条件
copper(II) ferrite; potassium tert-butylate in N,N-dimethyl-formamide T=155°C; 24 h; Inert atmosphere;
参考文献
Panda, Niranjan; Jena, Ashis Kumar; Mohapatra, Sasmita; Rout, Smruti Ranjan
Tetrahedron Letters, 2011 , vol. 52, # 16 p. 1924 - 1927
反应条件
copper(II) ferrite; potassium tert-butylate in N,N-dimethyl-formamide T=155°C; 24 h; Inert atmosphere;
参考文献
Panda, Niranjan; Jena, Ashis Kumar; Mohapatra, Sasmita; Rout, Smruti Ranjan
Tetrahedron Letters, 2011 , vol. 52, # 16 p. 1924 - 1927
反应条件
copper; caesium carbonate in n-butyronitrile 7 h; RefluxInert atmosphere;
参考文献
Zhu, Rui; Xing, Lixin; Wang, Xinyan; Cheng, Chuanjie; Su, Deyong; Hu, Yuefei
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 9 p. 1253 - 1257
反应条件
hydrogenchloride Reflux;
参考文献
More, Uttam A.; Joshi, Shrinivas D.; Aminabhavi, Tejraj M.; Gadad, Andanappa K.; Nadagouda, Mallikarjuna N.; Kulkarni, Venkatrao H.
European Journal of Medicinal Chemistry, 2014 , vol. 71, p. 199 - 218
反应条件
1: hydrogenchloride 2: acetic acid View Scheme
参考文献
Joshi, Shrinivas D.; More, Uttam A.; Dixit, Sheshagiri R.; Korat, Haresh H.; Aminabhavi, Tejraj M.; Badiger, Aravind M.
Medicinal Chemistry Research, 2014 , vol. 23, # 3 p. 1123 - 1147
反应条件
hydrazine hydrate in ethanol 3 h;
参考文献
Artico, Marino; Corelli, Federico; Massa, Silvio; Stefancich, Giorgio; Avigliano, Luciana; et al.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 4 p. 802 - 806
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=0°C; 2 h; 2: With hydrogenchloride in tetrahydrofuran; water; ethyl acetate T=0°C;
参考文献
LUPIN LIMITED
Patent: WO2009/109999 A1, 2009 ;
Location in patent: Page/Page column 63 ;
WO 2009/109999 A1
反应条件
1: 92 percent / NaBH4, CaCl2 / tetrahydrofuran / Ambient temperature 2: 87 percent / pyridinium chlorochromate (PCC) / CH2Cl2 / 1.5 h / Ambient temperature View Scheme
参考文献
Artico; Silvestri; Stefancich; Avigliano; Di Giulio; Maccarrone; Agostinelli; Mondovi; Morpurgo
European Journal of Medicinal Chemistry, 1992 , vol. 27, # 3 p. 219 - 228
