dimethylsulfone T=150°C; 1 h;

in diethylene glycol dimethyl ether 0.191667 h; 225 deg C -> 185 deg C;

1: 1.) thionyl chloride / 1.) -10 to -15 deg C, 40 min, 2.) -10 deg C - room temperature, 2 h, reflux, 21 h 2: 87 percent / bis-(2-methoxy-ethyl) ether / 0.19 h / 225 deg C -> 185 deg C View Scheme