2-溴-5-(三氟甲氧基)苯甲醛合成路线 （共 3 条）
反应条件
1: With hydrogen bromide
0.25 h; Heating;
2: With hydrogen bromide; copper(I) bromide; sodium nitrite
0.75 h; Heating;
参考文献
Leconte, Stephane; Ruzziconi, Renzo
Journal of Fluorine Chemistry, 2002 , vol. 117, # 2 p. 167 - 172
反应条件
1.1: 85 percent / toluene / 24 h / Heating
2.1: BuLi / tetrahydrofuran; hexane / 6 h / -75 °C
2.2: 85 percent / tetrahydrofuran; hexane / 0.75 h / -75 °C
3.1: aq. HBr / 0.25 h / Heating
3.2: 88 percent / aq. NaNO2; HBr; CuBr / 0.75 h / Heating
View Scheme
参考文献
Leconte, Stephane; Ruzziconi, Renzo
Journal of Fluorine Chemistry, 2002 , vol. 117, # 2 p. 167 - 172
反应条件
1.1: BuLi / tetrahydrofuran; hexane / 6 h / -75 °C
1.2: 85 percent / tetrahydrofuran; hexane / 0.75 h / -75 °C
2.1: aq. HBr / 0.25 h / Heating
2.2: 88 percent / aq. NaNO2; HBr; CuBr / 0.75 h / Heating
View Scheme
参考文献
Leconte, Stephane; Ruzziconi, Renzo
Journal of Fluorine Chemistry, 2002 , vol. 117, # 2 p. 167 - 172
