potassium carbonate in N,N-dimethyl-formamide 0.333333 h;

1: 1,3-thiazole With n-butyllithium in tetrahydrofuran; hexanes T=-78°C; Inert atmosphere; 2: dimethyl-disulfide in tetrahydrofuran; hexanes 2 h;

potassium iodide in methanol

hydrogenchloride in ethanol 1.) 50 to 80 deg C, 45 min, 2.) reflux, 15 min;

NiO2 in benzene

ammonia; lithium; ammonium chloride 1,) Et2O, -78 to -70 deg C, 2.) -70 deg C; Yield given. Multistep reaction;

1: 2-Methylthio-1,3-thiazole With 3-chloroprop-1-ene; trifluoroacetic acid; cobalt(II) dibromide; zinc in acetonitrile T=35°C; 2: para-iodobenzonitrile With bis-triphenylphosphine-palladium(II) chloride in N,N-dimethyl-formamide; acetonitrile T=35°C; Barbier type reaction;

1: 2-Methylthio-1,3-thiazole With 3-chloroprop-1-ene; trifluoroacetic acid; cobalt(II) dibromide; zinc in acetonitrile T=35°C; 2: para-iodoanisole With bis-triphenylphosphine-palladium(II) chloride in N,N-dimethyl-formamide; acetonitrile T=35°C; Barbier type reaction;