4-氨基-1-苄基哌啶合成路线

参考文献

Japan Tobacco, Inc.
Patent: US6235730 B1, 2001 ;

50541-93-04-氨基-1-苄基哌啶+

75-09-2二氯甲烷+

24424-99-5二碳酸二叔丁酯

73889-19-71-苄基-4-(Boc-氨基)哌啶

参考文献

Hoechst Aktiengesellschaft
Patent: US5374731 A1, 1994 ;

50541-93-04-氨基-1-苄基哌啶

5810-56-0N-哌啶-4-基-乙酰胺

参考文献

Manetti, Dina; Martini, Elisabetta; Ghelardini, Carla; Dei, Silvia; Galeotti, Nicoletta; Guandalini, Luca; Romanelli, Maria Novella; Scapecchi, Serena; Teodori, Elisabetta; Bartolini, Alessandro; Gualtieri, Fulvio
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 14 p. 2303 - 2306

50541-93-04-氨基-1-苄基哌啶

130260-03-6

参考文献

Valenta, Vladimir; Holubek, Jiri; Svatek, Emil; Matousova, Oluse; Metysova, Jirina; Protiva, Miroslav
Collection of Czechoslovak Chemical Communications, 1990 , vol. 55, p. 1297 - 1310

50541-93-04-氨基-1-苄基哌啶

132740-50-21-环戊基-4-氨基哌啶

参考文献

Huang; Luedtke; Freeman; Wu; Mach
Journal of Medicinal Chemistry, 2001 , vol. 44, # 11 p. 1815 - 1826

50541-93-04-氨基-1-苄基哌啶

309251-30-7

参考文献

Huang; Hammond; Wu; Mach
Journal of Medicinal Chemistry, 2001 , vol. 44, # 25 p. 4404 - 4415

50541-93-04-氨基-1-苄基哌啶+

97-72-3异丁酸酐

312924-69-9N-(1-苄基哌啶-4-基)异丁酰胺

参考文献

AstraZeneca AB
Patent: US2008/139613 A1, 2008 ;
Location in patent: Page/Page column 10 ;
US 20080139613 A1

50541-93-04-氨基-1-苄基哌啶+

79-30-1异丁酰氯

312924-69-9N-(1-苄基哌啶-4-基)异丁酰胺

参考文献

Barber, Christopher G.; Blakemore, David C.; Chiva, Jean-Yves; Eastwood, Rachel L.; Middleton, Donald S.; Paradowski, Kerry A.
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 5 p. 1499 - 1503

50541-93-04-氨基-1-苄基哌啶+

79-31-2异丁酸

312924-69-9N-(1-苄基哌啶-4-基)异丁酰胺

参考文献

Fan, Xing; Zhang, Hu-Shan; Chen, Li; Long, Ya-Qiu
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 7 p. 2827 - 2840

50541-93-04-氨基-1-苄基哌啶+

2969-81-54-溴丁酸乙酯

340962-88-11-(1-苄基哌啶-4-基)吡咯烷-2-酮

参考文献

Sasmal, Sanjita; Balaji, Gade; Kanna Reddy, Hariprasada R.; Balasubrahmanyam; Srinivas, Gujjary; Kyasa, Shivakumar; Sasmal, Pradip K.; Khanna, Ish; Talwar, Rashmi; Suresh; Jadhav, Vikram P.; Muzeeb, Syed; Shashikumar, Dhanya; Harinder Reddy; Sebastian; Frimurer, Thomas M.; Rist, ystein; Elster, Lisbeth; Hoegberg, Thomas
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 9 p. 3157 - 3162