3-氨基-2-乙基-4(3H)-喹唑啉酮合成路线 （共 26 条）
反应条件
lead(IV) acetate 1.) CH2Cl2, -25 to -20 deg C, 5 min, 2.) CH2Cl2, -25 deg C to room temp., 25 min; Yield givenMultistep reaction. Yields of byproduct given;
参考文献
Atkinson, Robert S.; Ulukanli, Sabri
Journal of the Chemical Society. Perkin Transactions 2, 1999 , # 4 p. 771 - 776
反应条件
lead(IV) acetate 1.) CH2Cl2, -25 to -20 deg C, 5 min, 2.) CH2Cl2, -25 deg C to room temp., 25 min; Yield givenMultistep reaction. Yields of byproduct given;
参考文献
Atkinson, Robert S.; Ulukanli, Sabri
Journal of the Chemical Society. Perkin Transactions 2, 1999 , # 4 p. 771 - 776
反应条件
in dichloromethane T=-20°C;
参考文献
Atkinson, Robert S.; Edwards, Paul J.; Thomson, Gordon A.
Journal of the Chemical Society, Chemical Communications, 1992 , # 17 p. 1256 - 1257
反应条件
in chloroform-d1 T=-20°C; Title compound not separated from byproducts;
参考文献
Atkinson, Robert S.; Kelly, Brian J.
Journal of the Chemical Society, Chemical Communications, 1987 , # 18 p. 1362 - 1363
反应条件
in dichloromethane T=-23 - 20°C;
参考文献
Davies, Stephen G.; Ling, Kenneth B.; Roberts, Paul M.; Russell, Angela J.; Thomson, James E.; Woods, Philip A.
Tetrahedron, 2010 , vol. 66, # 34 p. 6806 - 6813
反应条件
lead(IV) acetate in dichloromethane
参考文献
Atkinson, Robert S.; Kelly, Brian J.
Journal of the Chemical Society, Chemical Communications, 1989 , # 13 p. 836 - 837
反应条件
1: T=75 - 105°C; Neat (no solvent);
2: With hydrazine hydrate in ethanol
T=75°C; 1.08333 h; Reflux;
参考文献
Davies, Stephen G.; Ling, Kenneth B.; Roberts, Paul M.; Russell, Angela J.; Thomson, James E.; Woods, Philip A.
Tetrahedron, 2010 , vol. 66, # 34 p. 6806 - 6813
反应条件
hydrazine in ethanol
1 h; Heating;
参考文献
Leiby, Robert W.
Journal of Organic Chemistry, 1985 , vol. 50, # 16 p. 2926 - 2929
反应条件
sodium hydroxide in methanol
1 h; Heating;
参考文献
Smith, Keith; El-Hiti, Gamal A,; Abdo, Mohamed A.; Abdel-Megeed, Mohamed F.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 8 p. 1029 - 1034
反应条件
hydrazine hydrate in methanol
6 h; Heating;
参考文献
Kumar, Atul; Singh, S.; Saxena, A. K.; Shanker, K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 443 - 447
