5-甲氧基苯并呋喃-2-羧酸 乙酯合成路线 （共 11 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=140°C; 1.5 h; RefluxMolecular sieve;
参考文献
Korea Institute of Science and Technology; HANMI HOLDINGS CO., LTD
Patent: US2011/124888 A1, 2011 ;
Location in patent: Page/Page column 6 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide T=90°C; 48 h;
参考文献
BIOLIPOX AB
Patent: WO2008/110793 A1, 2008 ;
Location in patent: Page/Page column 110 ;
反应条件
ethanol; sodium ethanolate
参考文献
Mohr, Peter; Nettekoven, Matthias; Plancher, Jean-Marc; Richter, Hans; Roche, Olivier; Takahashi, Tadakatsu; Taylor, Sven
Patent: US2009/29976 A1, 2009 ;
Location in patent: Page/Page column 18 ;
US 20090029976 A1
反应条件
potassium carbonate in butanone 4 h; Heating;
参考文献
Friedman; Toyne; Goodby; Hird
Journal of Materials Chemistry, 2001 , vol. 11, # 11 p. 2759 - 2772
反应条件
1: lithium aluminium tetrahydride / N,N-dimethyl-formamide; tetrahydrofuran / 0.17 h / 0 °C 2: phosphorus tribromide / N,N-dimethyl-formamide / 1 h / 0 °C View Scheme
参考文献
Korea Institute of Science and Technology; HANMI HOLDINGS CO., LTD
Patent: US2011/124888 A1, 2011 ;
反应条件
potassium hydroxide in ethanol 0.75 h; Heating;
参考文献
Mohr, Peter; Nettekoven, Matthias; Plancher, Jean-Marc; Richter, Hans; Roche, Olivier; Takahashi, Tadakatsu; Taylor, Sven
Patent: US2009/29976 A1, 2009 ;
Location in patent: Page/Page column 18 ;
US 20090029976 A1
反应条件
1.1: aq. KOH / ethanol 2.1: thionyl chloride / benzene 2.2: ammonia / tetrahydrofuran View Scheme
参考文献
Friedman; Toyne; Goodby; Hird
Journal of Materials Chemistry, 2001 , vol. 11, # 11 p. 2759 - 2772
反应条件
1: boron tribromide / dichloromethane / -78 - 20 °C 2: PS 4-(methylazoamino)phenoxymethyl resin / dichloromethane / 2 h / 20 °C View Scheme
参考文献
SENOMYX, INC.; TACHDJIAN, Catherine; LI, Xiaodong; KARANEWSKY, Donald S.; FOTSING, Joseph; PATRON, Andrew; DARMOHUSODO, Vincent; SELCHAU, Victor; CHING, Brett
Patent: WO2011/159781 A2, 2011 ;
WO 2011/159781 A2
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran; diethyl ether
T=0°C;
2: With sodium hydrogencarbonate in water
参考文献
Korea Institute of Science and Technology; HANMI HOLDINGS CO., LTD
Patent: US2011/124888 A1, 2011 ;
Location in patent: Page/Page column 6 ;
反应条件
ethanethiol; aluminium trichloride
参考文献
SmithKline Beecham Corporation
Patent: US6518267 B1, 2003 ;
US 6518267 B1
