8-甲氧基-2-甲基喹啉-4-醇合成路线 （共 6 条）
反应条件
hydrogen; kieselguhr; nickel in methanol T=120°C; P=75005.9 Torr; 16 h;
参考文献
Gildemeister; Knorr; Mildenberger; Salbeck
1982 , vol. No. 9, p. 1656 - 1676
反应条件
acidic styrol NKC-9 resin in neat (no solvent)
T=20°C; Combes Quinoline Synthesis; 0.025 h; Microwave irradiation;
参考文献
Yuan, Shizhen; Zhang, Kehua; Xia, Jingjing
Asian Journal of Chemistry, 2013 , vol. 25, # 10 p. 5535 - 5538
反应条件
lithium diisopropyl amide in tetrahydrofuran
0 deg C to room temp., 8-12 h;
参考文献
Chong, R.J.; Siddiqui, M.A.; Snieckus, V.
Tetrahedron Letters, 1986 , vol. 27, # 44 p. 5323 - 5326
反应条件
1: 95 percent / Ambient temperature; for 2-7 days
2: 95 percent / LDA / tetrahydrofuran / 0 deg C to room temp., 8-12 h
View Scheme
参考文献
Chong, R.J.; Siddiqui, M.A.; Snieckus, V.
Tetrahedron Letters, 1986 , vol. 27, # 44 p. 5323 - 5326
反应条件
0.05 h; microwave irradiation;
参考文献
Nadaraj; Selvi, S. Thamarai
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2007 , vol. 46, # 7 p. 1203 - 1207
反应条件
1: 80 percent / H2 / 50 percent Ni/kieselguhr / methanol / 16 h / 120 °C / 75005.9 Torr
2: 80 percent / triethyl amine / CHCl3 / 6 h / 50 °C
View Scheme
参考文献
Gildemeister; Knorr; Mildenberger; Salbeck
1982 , vol. No. 9, p. 1656 - 1676
