2-氨基-6-硝基苯甲酸合成路线 （共 29 条）
反应条件
1: With bromine; sodium hydroxide in water T=-5 - 45°C; 0.583333 h; 2: With hydrogenchloride in water T=0°C;
参考文献
DOW AGROSCIENCES LLC
Patent: US2011/301178 A1, 2011 ;
Location in patent: Page/Page column 7 ;
反应条件
1: With potassium hydroxide; bromine in water T=0 - 100°C; 1.58333 h; 2: With hydrogenchloride; water T=0°C; 1 h;
参考文献
Muller, George; Man, Hon-Wah; Cohen, Benjamin M.; Li, Ying; Xu, Jean; Leong, William W.
Patent: US2012/232100 A1, 2012 ;
Location in patent: Page/Page column 24 ;
反应条件
1: With sodium hypochlorite; water; sodium hydroxide T=25 - 30°C; pH=12; 2 h; 2: With hydrogenchloride in water T=5 - 10°C; pH=1.8; Product distribution / selectivity;
参考文献
SYNGENTA PARTICIPATIONS AG; MURUDI, Vikrant; SHYADLIGERI, Ashok Shankarappa; MISHRA, Brijnandan Premnath; LUGINBUEHL, Markus Adolf; FUERST, Maren
Patent: WO2011/98386 A1, 2011 ;
Location in patent: Page/Page column 4-5 ;
反应条件
(NH4)2S in ethanol 1.5 h; Reflux;
参考文献
GE HEALTHCARE LIMITED; WOODCRAFT, John; JONES, Clare; GAETA, Alessandra; TRIGG, William; JONES, Paul; PLANT, Stuart; JACKSON, Alexander
Patent: WO2011/42529 A1, 2011 ;
Location in patent: Page/Page column 27 ;
参考文献
Saari; Schwering
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 4 p. 1253 - 1255
反应条件
1: urea / acetic acid / 4 h / 140 °C 2: sodium hydroxide; sodium hypochlorite / water / 2 h / 20 °C View Scheme
参考文献
Bhowmik, Subhendu; Pandey, Garima; Batra, Sanjay
Chemistry - A European Journal, 2013 , vol. 19, # 32 p. 10487 - 10491
参考文献
Curtius; Semper
Chemische Berichte, 1913 , vol. 46, p. 1170
反应条件
alkaline aqueous potassium hypobromite
参考文献
Spring; Woods
Journal of the Chemical Society, 1945 , p. 625,627
反应条件
1: chloroform 2: aq. barium hydroxide solution / Erhitzen View Scheme
参考文献
Curtius; Semper
Chemische Berichte, 1913 , vol. 46, p. 1170
反应条件
potassium hypobromide
参考文献
Kahn
Chemische Berichte, 1902 , vol. 35, # 472 p. 3866
