L-(-)-二对甲氧基苯甲酰酒石酸合成路线 （共 5 条）
反应条件
1: With potassium carbonate in methanol; water T=50°C; 1.5 h; 2: With hydrogenchloride in methanol; water Product distribution / selectivity;
参考文献
Aventis Pharmaceuticals, Inc.; Hoechst Marion Roussel Deutschland GmbH
Patent: EP1734037 A2, 2006 ;
Location in patent: Page/Page column 9; 41 ;
反应条件
1: With sodium hydroxide in tetrahydrofuran; water T=40°C; 2: With sulfuric acid in tetrahydrofuran; water Heating / reflux; Product distribution / selectivity;
参考文献
Aventis Pharmaceuticals, Inc.; Hoechst Marion Roussel Deutschland GmbH
Patent: EP1734037 A2, 2006 ;
Location in patent: Page/Page column 11; 41-42 ;
参考文献
Aventis Pharmaceuticals, Inc.; Hoechst Marion Roussel Deutschland GmbH
Patent: EP1734037 A2, 2006 ;
Location in patent: Page/Page column 33-37 ;
反应条件
1: in ethanol; water T=15 - 65°C; 1.5 h; 2: With potassium carbonate in water T=25°C; pH=8 - 9; 0.5 h;
参考文献
CIPLA LIMITED; RAO, Dharmaraj, Ramachandra; KANKAN, Rajendra, Narayanrao; PHULL, Manjinder, Singh; SAWANT, Ashwini, Amol; CURTIS, Philip, Anthony
Patent: WO2011/7123 A1, 2011 ;
Location in patent: Page/Page column 12 ;
反应条件
in ethanol; water T=15 - 65°C;
参考文献
CIPLA LIMITED; RAO, Dharmaraj, Ramachandra; KANKAN, Rajendra, Narayanrao; PHULL, Manjinder, Singh; SAWANT, Ashwini, Amol; CURTIS, Philip, Anthony
Patent: WO2011/7123 A1, 2011 ;
Location in patent: Page/Page column 12 ;
