4,7-二氯-2-甲基喹啉合成路线 （共 10 条）
反应条件
trichlorophosphate T=120°C; 1 h; Heating;
参考文献
De; Byers; Krogstad
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 1 p. 315 - 320
反应条件
copper(l) chloride; magnesium chloride in diethyl ether T=23°C; Grignard Reaction; 12 h; Inert atmosphere;
参考文献
Larionov, Oleg V.; Stephens, David; Mfuh, Adelphe; Chavez, Gabriel
Organic Letters, 2014 , vol. 16, # 3 p. 864 - 867
反应条件
1: 120 - 130 °C / Behandeln mit Paraldehyd; Trennung der Isomeren ueber die Pikrate 2: monoperoxyphthalic acid; diethyl ether; aqueous ammonia 3: phosphoryl chloride View Scheme
参考文献
De; Byers; Krogstad
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 1 p. 315 - 320
反应条件
1: 55 percent / diphenyl ether / 0.5 h / Heating 2: 80 percent / POCl3 / 1 h / 120 °C / Heating View Scheme
参考文献
Luo, Wei; Liu, Yang; Wang, Jian; Guo, Chun; Lu, Wei-Qiang; Cui, Kun-Qiang
Medicinal Chemistry Research, 2012 , vol. 21, # 10 p. 3073 - 3079,7
参考文献
Spivey; Curd
Journal of the Chemical Society, 1949 , p. 2656,2660
反应条件
1: monoperoxyphthalic acid; diethyl ether; aqueous ammonia 2: phosphoryl chloride View Scheme
参考文献
Spivey; Curd
Journal of the Chemical Society, 1949 , p. 2656,2660
反应条件
1: sulfuric acid; potassium nitrate 2: SnCl2; aqueous HCl 3: palladium/charcoal; ethanol; sodium acetate / Hydrogenation View Scheme
参考文献
Sen; Basu
Journal of the Indian Chemical Society, 1957 , vol. 34, p. 836
参考文献
Giller,S.A. et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1976 , vol. 12, p. 217 - 219
Khimiya Geterotsiklicheskikh Soedinenii, 1976 , vol. 12, p. 253 - 255
反应条件
zinc(II) chloride T=135 - 155°C;
参考文献
Sukhova, N. M.; Lidak, M. Yu.; Kruzmetra, L. V.; Zile, A. Ya
Pharmaceutical Chemistry Journal, 1982 , vol. 16, # 12 p. 883 - 885
Khimiko-Farmatsevticheskii Zhurnal, 1982 , vol. 16, # 12 p. 1463 - 1466
反应条件
hydrazine hydrate
T=20 - 150°C; 0.0833333 h; microwave irradiation in sealed tube;
参考文献
Gemma, Sandra; Kukreja, Gagan; Tripaldi, Pierangela; Altarelli, Maria; Bernetti, Matteo; Franceschini, Silvia; Savini, Luisa; Campiani, Giuseppe; Fattorusso, Caterina; Butini, Stefania
Tetrahedron Letters, 2008 , vol. 49, # 13 p. 2074 - 2077
