4-氯-6-甲氧基-2-甲基喹啉合成路线 （共 11 条）
反应条件
1: With trichlorophosphate T=105°C; 2 h; 2: With sodium hydrogencarbonate in water Cooling with ice;
参考文献
Thomas; Adhikari, Airody Vasudeva; Shetty, N. Suchetha
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 9 p. 3803 - 3810
反应条件
trichlorophosphate T=0 - 80°C;
参考文献
Kakadiya, Rajesh; Dong, Huajin; Kumar, Amit; Narsinh, Dodia; Zhang, Xiuguo; Chou, Ting-Chao; Lee, Te-Chang; Shah, Anamik; Su, Tsann-Long
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2285 - 2299
反应条件
1: methanol / 7 h / 40 °C 2: diphenylether / 0.5 h / |Reflux 3: trichlorophosphate / 3 h / |Reflux View Scheme
参考文献
Desai; Desai, Pratibha; Machhi, Dilip; Patel, Dinesh
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1996 , vol. 35, # 8 p. 871 - 873
反应条件
1: diphenylether / 0.5 h / |Reflux 2: trichlorophosphate / 3 h / |Reflux View Scheme
参考文献
Luo, Wei; Liu, Yang; Wang, Jian; Guo, Chun; Lu, Wei-Qiang; Cui, Kun-Qiang
Medicinal Chemistry Research, 2012 , vol. 21, # 10 p. 3073 - 3079,7
参考文献
Conrad; Limpach
Patent: DE42276 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 1, p. 204
Full Text Show Details
Conrad; Limpach
Chemische Berichte, 1888 , vol. 21, p. 1652
参考文献
Renfrew
Journal of the American Chemical Society, 1946 , vol. 68, p. 1433,1435
反应条件
hydrogenchloride; tin; water Erhitzen der Reaktionsprodukts mit wss. Natronlauge;
参考文献
Rubzow
Zhurnal Obshchei Khimii, 1943 , vol. 13, p. 593,600
Chem.Abstr., 1945 , p. 705
反应条件
1: With phenol T=180°C; 1 h; 2: With ammonia T=180°C; 5 h; 3: With sodium hydroxide in water T=20°C;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 18, # 6 p. 2285 - 2299
反应条件
hydrazine hydrate
T=20 - 150°C; 0.0833333 h; microwave irradiation in sealed tube;
参考文献
Gemma, Sandra; Kukreja, Gagan; Tripaldi, Pierangela; Altarelli, Maria; Bernetti, Matteo; Franceschini, Silvia; Savini, Luisa; Campiani, Giuseppe; Fattorusso, Caterina; Butini, Stefania
Tetrahedron Letters, 2008 , vol. 49, # 13 p. 2074 - 2077
参考文献
Koenigs; v. Loesch
Journal fuer Praktische Chemie (Leipzig), 1935 , vol. <2> 143, p. 59,62
