Li[B(C6F5)4]*2.5(Et2O); dihydrogen peroxide; oxalic acid in 1,2-dichloro-ethane T=20°C; Baeyer-Villiger Ketone Oxidation; 1.5 h;

sodium tetrahydroborate in methanol T=20°C; reductive cyclization;

2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in benzene 0.5 h; Heating;

1.1: NaH / dimethylsulfoxide 1.2: 88 percent / dimethylsulfoxide / 20 °C 2.1: 95 percent / NaBH4 / methanol / 20 °C View Scheme

1: NaI; trifluoroacetic anhydride / acetone / 0.25 h / -50 °C 2: 99 percent / Bu3SnH; AIBN / benzene / 0.5 h / Heating View Scheme

1: ammonium chloride; zinc / methanol / 6 h / Reflux 2: dichloro bis(acetonitrile) palladium(II); silver hexafluoroantimonate; urea hydrogen peroxide addition compound; (S)-tBu-Phox / tetrahydrofuran / -40 °C View Scheme

1: zinc/copper couple; trichlorophosphate / diethyl ether / 10 h / 40 °C 2: ammonium chloride; zinc / methanol / 6 h / Reflux 3: dichloro bis(acetonitrile) palladium(II); silver hexafluoroantimonate; urea hydrogen peroxide addition compound; (S)-tBu-Phox / tetrahydrofuran / -40 °C View Scheme

lithium tri(t-butyl)hydroborate T=-70°C; Multistep, regioselective reduction, add. of agent (inversion), var. temp.; Product distribution;