反应条件
1: 97 percent / chlorotrimethylsilane, sodium iodide / acetonitrile / 1.5 h / 70 °C
2: 1.) hexamethylphosphoramide (HMPA) / 1.) RT, 45 min, 2.) 0 deg C, 30 min
3: 88 percent / diethyl ether / 10 h / 0 °C
4: 1.) catecholborane, H2O, 2.) NaI, chloramine-T / 1.) 18 h, 2.) THF, H2O, 15 min
View Scheme
参考文献
Knapp, F. F.; Goodman, M. M.; Kabalka, G. W.; Sastry, K. A. R.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 1 p. 94 - 97
