Hosseini, Yaser; Rastgar, Saeed; Zerrin Heren; Orhan Bueyuekguengoer; Pesyan, Nader Noroozi
Journal of the Chinese Chemical Society, 2011 , vol. 58, # 3 p. 309 - 318
1: {6-[2-tert-butyl-5-(4-fluoro-phenyl)-3H-imidazol-4-yl]-3-nitro-pyridin-2-yl}-(2,2-dimethyl-propyl)-amine With hydrogen; palladium 10 on activated carbon in ethanol
2: bromocyane in ethanol; water
T=20°C;
3: With sodium hydrogencarbonate in ethanol; water
Saturated solution; Product distribution / selectivity;
参考文献
ELI LILLY AND COMPANY
Patent: WO2005/75478 A1, 2005 ;
Location in patent: Page/Page column 49 ;
WO 2005/075478 A1
