1: 74 percent / Et3N, H2 / 5percent Pd/C / methanol / 16 h / Ambient temperature 2: Ac2O/DMSO / 20 h / Ambient temperature 3: NaBH4 / ethanol; H2O / Ambient temperature 4: 0.4N HCl / 1.) 95 deg C, 90 min; 2.) RT, 30 min 5: pyridine / 20 h / 20 °C View Scheme

1: 74 percent / Et3N, H2 / 5percent Pd/C / methanol / 16 h / Ambient temperature 2: Ac2O/DMSO / 20 h / Ambient temperature 3: NaBH4 / ethanol; H2O / Ambient temperature 4: 0.4N HCl / 1.) 95 deg C, 90 min; 2.) RT, 30 min 5: pyridine / 20 h / 20 °C 6: 65 percent / CF3SO2OSiMe3, hexamethyldisilazane / CH2Cl2 / 20 h / Ambient temperature 7: 97 percent / CH3ONa / methanol / Ambient temperature View Scheme

tributyl-amine; tris-fac-Ir(ppy)3; diethyl-1,4-dihydro-2,6-dimethyl-3,5-pyridine dicarboxylate in acetonitrile T=25 - 30°C; 20 h; Inert atmosphereIrradiation;

2,2'-azo-bisisobutyronitrile; allyltributylstannane in toluene T=80°C;

2,2'-azo-bisisobutyronitrile in toluene T=80°C;