1: 32 percent / H2, Et3N / 10percent Pd/C / aq. ethanol / 5 h / 1471.02 Torr 2: 2.2 g / Cu(OAc)2, quinoline / 3 h / 190 - 210 °C View Scheme

hydrogenchloride anschliessend Erwaermen mit Acetessigsaeure-benzylester, Essigsaeure, Zink-Pulver und Ammoniumacetat;

1: 54 percent / H2, Et3N / 10percent Pd/C / aq. ethanol / 5 h / 1471.02 Torr 2: 96 percent / Cu(OAc)2, quinoline / 3 h / 190 - 210 °C 3: 98 percent / 8percent aq. NaOH / aq. ethanol / 1 h / Heating 4: 85 percent / H2O / 100 °C View Scheme

hydrogen; triethylamine; palladium on activated charcoal in ethanol P=1471.02 Torr; 5 h;

ethanol; nickel T=100°C; P=73550.8 Torr; Hydrogenation;