乙二酸 1-(1,1-二甲基乙基) 2-乙酯合成路线 （共 9 条）
反应条件
1: NH4OH / ethanol 2: (CF3CO)2O / pyridine 3: aq. NH3 View Scheme
参考文献
Carpino,L.A.
Journal of the American Chemical Society, 1960 , vol. 82, p. 2725 - 2727
反应条件
1: N2H4*H2O / CH2Cl2 2: (i) NaNO2, aq. HCl, Et2O, (ii) /BRN= 906698/ View Scheme
参考文献
Carpino,L.A.
Journal of Organic Chemistry, 1964 , vol. 29, p. 2820 - 2824
反应条件
ammonia in ethanol; water T=0°C;
参考文献
Xu, Yingju; McLaughlin, Mark; Bolton, Emily N.; Reamer, Robert A.
Journal of Organic Chemistry, 2010 , vol. 75, # 24 p. 8666 - 8669
反应条件
1: NH4OH / ethanol 2: (CF3CO)2O / pyridine View Scheme
参考文献
Carpino,L.A.
Journal of the American Chemical Society, 1960 , vol. 82, p. 2725 - 2727
反应条件
1: NH4OH / ethanol 2: (CF3CO)2O / pyridine 3: dimethylformamide View Scheme
参考文献
Carpino,L.A.
Journal of the American Chemical Society, 1960 , vol. 82, p. 2725 - 2727
反应条件
pyridine in dichloromethane
T=0 - 20°C;
参考文献
Xu, Yingju; McLaughlin, Mark; Bolton, Emily N.; Reamer, Robert A.
Journal of Organic Chemistry, 2010 , vol. 75, # 24 p. 8666 - 8669
参考文献
Crandall,J.K. et al.
Journal of Organic Chemistry, 1974 , vol. 39, # 15 p. 2172 - 2175
反应条件
1: N2H4*H2O / CH2Cl2
2: (i) NaNO2, aq. HCl, Et2O, (ii) /BRN= 906698/
3: (i) NaH, DMF, (ii) N-hydroxy-2,4,6-trimethyl-benzamide
View Scheme
参考文献
Carpino,L.A.
Journal of Organic Chemistry, 1964 , vol. 29, p. 2820 - 2824
反应条件
1: NH4OH / ethanol
2: (CF3CO)2O / pyridine
3: CH2Cl2
View Scheme
参考文献
Carpino,L.A.
Journal of the American Chemical Society, 1960 , vol. 82, p. 2725 - 2727
